Clinical comparison of intravenous thrombolysis and bridging artery thrombectomy in hyperacute ischemic stroke with unknown time of onset

Bai Qingke; Zheng Ping; Zhang Jianying; Zhao Zhenguo

doi:10.5114/aoms/143513

Clinical comparison of intravenous thrombolysis and bridging artery thrombectomy in hyperacute ischemic stroke with unknown time of onset

Arch Med Sci. 2021 Nov 9;17(6):1804-1810. doi: 10.5114/aoms/143513. eCollection 2021.

Authors

Bai Qingke¹, Zheng Ping², Zhang Jianying¹, Zhao Zhenguo³

Affiliations

¹ Department of Neurology, Pudong Institute for Health Development, Shanghai, China.
² Department of Neurosurgery, Pudong Institute for Health Development, Shanghai, China.
³ Department of Radiography, Pudong Institute for Health Development, Shanghai, China.

Abstract

Introduction: The aim of the study was to explore the clinical efficacy and safety of intravenous thrombolysis and bridging artery thrombectomy for hyperacute ischemic stroke with unknown onset time.

Methods: One hundred and twenty-eight patients with hyperacute cerebral infarction and without a clear time of onset were randomly divided into intravenous thrombolysis (n = 66) and bridging artery thrombectomy groups (n = 62).

Results: In the intravenous thrombolysis group, 37 patients' vessels had recanalization, 32 patients' 24-hour National Institute of Health Stroke Scale (NIHSS) score improved, and 42 patients' 90-day modified Rankin Scale (mRS) score was good. In the bridging artery thrombectomy group, 62 patients' vessels had recanalization, 28 patients' 24-hour NIHSS score improved, and 38 patients' 90-day mRS score was good.

Conclusions: The benefits and adverse events between intravenous thrombolysis and bridging artery thrombectomy for ischemic stroke with unknown time of onset are similar.

Keywords: cerebral infarction; intravenous thrombolysis; large intracranial artery occlusion; magnetic resonance imaging; solitaire thrombectomy.