Vestibular and postural impairment in congenital Cytomegalovirus infection

Virginia Corazzi; Stavros Hatzopoulos; Chiara Bianchini; Magdalena B Skarżyńska; Stefano Pelucchi; Piotr Henryk Skarżyński; Andrea Ciorba

doi:10.1016/j.ijporl.2021.111005

Vestibular and postural impairment in congenital Cytomegalovirus infection

Int J Pediatr Otorhinolaryngol. 2022 Jan:152:111005. doi: 10.1016/j.ijporl.2021.111005. Epub 2021 Dec 7.

Authors

Virginia Corazzi¹, Stavros Hatzopoulos¹, Chiara Bianchini¹, Magdalena B Skarżyńska², Stefano Pelucchi¹, Piotr Henryk Skarżyński³, Andrea Ciorba⁴

Affiliations

¹ ENT and Audiology Department, University Hospital of Ferrara, A. Moro 8, loc Cona, Ferrara, 44124, Italy.
² Institute of Sensory Organs, 1 Mokra Street, 05-830, Nadarzyn/Kajetany, Poland; Institute of Physiology and Pathology of Hearing, 10 Mochnackiego Street, 02-042, Warsaw, Poland.
³ Institute of Sensory Organs, 1 Mokra Street, 05-830, Nadarzyn/Kajetany, Poland; Institute of Physiology and Pathology of Hearing, 10 Mochnackiego Street, 02-042, Warsaw, Poland; Department of Heart Failure and Cardiac Rehabilitation, Medical University of Warsaw, 8 Kondratowicza Street, 03-242, Warsaw, Poland.
⁴ ENT and Audiology Department, University Hospital of Ferrara, A. Moro 8, loc Cona, Ferrara, 44124, Italy. Electronic address: andrea.ciorba@unife.it.

PMID: 34894538
DOI: 10.1016/j.ijporl.2021.111005

Abstract

Objectives: To describe the vestibular and postural impairment related to the congenital Cytomegalovirus infection (cCMV), including the inner ear damages CMV-induced.

Methods: A PRISMA systematic review was performed, with the PubMed, Embase, and Cinahl databases searched from inception through to March 2021; after the application of inclusion and exclusion criteria a total of 12 papers were included in this review.

Results: Vestibular and postural disorders have been reported in cCMV children, with a high variability of clinical manifestation. Presently, the available reported data on vestibular and postural impairment in cCMV children differ in terms of the sample size and the features of the studied populations.

Conclusion: At present, the vestibular and postural impairment in cCMV cases is underestimated; a complete vestibular assessment, a follow-up and management of all children affected by cCMV or, at least, of all cCMV patients showing sensorineural hearing loss, is recommended.

Keywords: Child; Congenital cytomegalovirus infection; Inner ear; Newborn; Postural impairment; Vestibular impairment.

Publication types

Review
Systematic Review

MeSH terms

Child
Cytomegalovirus Infections* / complications
Hearing Loss, Sensorineural* / diagnosis
Hearing Loss, Sensorineural* / etiology
Humans
Vestibule, Labyrinth*