Biosensors and nanotechnology for cancer diagnosis (lung and bronchus, breast, prostate, and colon): a systematic review

Fariborz Sharifianjazi; Azadeh Jafari Rad; Ameneh Bakhtiari; Firoozeh Niazvand; Amirhossein Esmaeilkhanian; Leila Bazli; Milad Abniki; Mohammad Irani; Amirhossein Moghanian

doi:10.1088/1748-605X/ac41fd

Biosensors and nanotechnology for cancer diagnosis (lung and bronchus, breast, prostate, and colon): a systematic review

Biomed Mater. 2021 Dec 24;17(1). doi: 10.1088/1748-605X/ac41fd.

Authors

Fariborz Sharifianjazi¹, Azadeh Jafari Rad², Ameneh Bakhtiari, Firoozeh Niazvand³, Amirhossein Esmaeilkhanian⁴, Leila Bazli⁵, Milad Abniki⁶, Mohammad Irani⁷, Amirhossein Moghanian⁸

Affiliations

¹ Department of Science and Technology, The University of Georgia, Tbilisi, Georgia.
² Department of Chemistry, Islamic Azad University, Omidiyeh Branch, Omidiyeh, Iran.
³ School of Medicine, Abadan University of Medical Sciences, Abadan, Iran.
⁴ Department of Materials and Metallurgical Engineering, Amirkabir University of Technology, Tehran, Iran.
⁵ School of Metallurgy and Materials Engineering, Iran University of Science and Technology (IUST), Narmak, Tehran, Iran.
⁶ Department of Resin and Additives, Institute for Color Science and Technology, Tehran, Iran.
⁷ Dentistry Clinical Research Development Unit, Alborz University of Medical Sciences, Karaj, Iran.
⁸ Department of Materials Engineering, Imam Khomeini International University, Qazvin 34149-16818, Iran.

PMID: 34891145
DOI: 10.1088/1748-605X/ac41fd

Abstract

The second cause of death in the world has been reported to be cancer, and it has been on the rise in recent years. As a result of the difficulties of cancer detection and its treatment, the survival rate of patients is unclear. The early detection of cancer is an important issue for its therapy. Cancer detection based on biomarkers may effectively enhance the early detection and subsequent treatment. Nanomaterial-based nanobiosensors for cancer biomarkers are excellent tools for the molecular detection and diagnosis of disease. This review reports the latest advancement and attainment in applying nanoparticles to the detection of cancer biomarkers. In this paper, the recent advances in the application of common nanomaterials like graphene, carbon nanotubes, Au, Ag, Pt, and Fe₃O₄together with newly emerged nanoparticles such as quantum dots, upconversion nanoparticles, inorganics (ZnO, MoS₂), and metal-organic frameworks for the diagnosis of biomarkers related to lung, prostate, breast, and colon cancer are highlighted. Finally, the challenges, outlook, and closing remarks are given.

Keywords: biomarkers; biosensors; cancer diagnosis; nanomaterials.

Publication types

Research Support, Non-U.S. Gov't
Review
Systematic Review

MeSH terms

Biosensing Techniques*
Bronchi
Colon
Humans
Lung
Male
Nanotechnology
Nanotubes, Carbon*
Neoplasms*
Prostate

Substances

Nanotubes, Carbon