The genus Schinus (Anacardiaceae): a review on phytochemicals and biological aspects

Nat Prod Res. 2022 Sep;36(18):4839-4857. doi: 10.1080/14786419.2021.2012772. Epub 2021 Dec 9.

Abstract

The genus Schinus belongs to family 'Anacardiaceae' and includes about 29 species originating from South America, distributed to Peru, Chile, Argentina, Brazil and Paraguay and cultivated in Egypt. Traditionally, Schinus plants are used to alleviate several and diverse diseases including rheumatism, hypertension, ulcers, gastric distress, menstrual disorders, gonorrhea, bronchitis, gingivitis, conjunctivitis, dysentery, wounds, urinary tract, and eye infections. Several phytochemical studies on the Schinus plants revealed presence of diverse bioactive compounds such as flavonoids, bioflavonoids, phenolic acids, tannins, catechins, terpenoids and essential oils. Besides, some Schinus species and their isolated active compounds showed important biological activities such as antibacterial, antifungal, insecticidal, antiparasitic, analgesic, cytotoxic, antitumor, antioxidant, antihypertensive, anti-inflammatory, antimycobacterial, anti-Parkinson, anti-allergic, antiviral, wound healing, chemoprotective, anthelmintic and hepatoprotective. This review attempts to summarize the phytochemical profile and biological activities of Schinus species that could guide researchers to undertake further investigation.

Keywords: Anacardiaceae; Schinus; antimicrobial; antioxidant; essential oils; extracts.

Publication types

  • Review

MeSH terms

  • Anacardiaceae* / chemistry
  • Anti-Bacterial Agents / chemistry
  • Anti-Bacterial Agents / pharmacology
  • Anti-Infective Agents*
  • Antifungal Agents / chemistry
  • Oils, Volatile* / chemistry
  • Phytochemicals
  • Plant Extracts / chemistry

Substances

  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Antifungal Agents
  • Oils, Volatile
  • Phytochemicals
  • Plant Extracts