Controlled versus free breathing for multiple-breath nitrogen washout in asthma

Blake M Handley; Jack Bozier; Edward Jeagal; Sandra Rutting; Robin E Schoeffel; Paul D Robinson; Gregory G King; Stephen Milne; Cindy Thamrin

doi:10.1183/23120541.00487-2021

Controlled versus free breathing for multiple-breath nitrogen washout in asthma

ERJ Open Res. 2021 Dec 6;7(4):00487-2021. doi: 10.1183/23120541.00487-2021. eCollection 2021 Oct.

Authors

Blake M Handley^{1

2

3}, Jack Bozier^{1

2

3}, Edward Jeagal^{1

4}, Sandra Rutting^{1

2}, Robin E Schoeffel², Paul D Robinson^{1

5}, Gregory G King^{1

2}, Stephen Milne^{1

6

7}, Cindy Thamrin^{1

7}

Affiliations

¹ Woolcock Institute of Medical Research, University of Sydney, Glebe, NSW, Australia.
² Dept of Respiratory Medicine, Royal North Shore Hospital, St Leonards, NSW, Australia.
³ These first authors contributed equally.
⁴ University of Technology Sydney, School of Life Sciences, Sydney, NSW, Australia.
⁵ Dept of Respiratory Medicine, The Children's Hospital at Westmead, Westmead, NSW, Australia.
⁶ Centre for Heart Lung Innovation, St Paul's Hospital and Division of Respiratory Medicine, University of British Columbia, Vancouver, BC, Canada.
⁷ These senior authors contributed equally.

Abstract

The lack of comparability in indices of ventilation heterogeneity between free- and controlled-breathing MBNW protocols is confirmed in asthma https://bit.ly/3lmri4A.