Effect of Wenshentiaojing Decoction on Hormone Level and Follicular Number in Patients with Menstrual Disorder of Polycystic Ovary Syndrome

Lanzhi Li; Ning Huang; Yanyan Qi; Yan Li; Lu Wang

doi:10.1155/2021/4975867

Effect of Wenshentiaojing Decoction on Hormone Level and Follicular Number in Patients with Menstrual Disorder of Polycystic Ovary Syndrome

Evid Based Complement Alternat Med. 2021 Nov 29:2021:4975867. doi: 10.1155/2021/4975867. eCollection 2021.

Authors

Lanzhi Li¹, Ning Huang², Yanyan Qi³, Yan Li⁴, Lu Wang⁵

Affiliations

¹ Department of Physical Examination, Yantaishan Hospital, Yantai 264000, China.
² Renal Interventional Department, Affiliated Qingdao Central Hospital, Qingdao University, Qingdao 266000, China.
³ PIVAS, Affiliated Qingdao Central Hospital, Qingdao University, Qingdao 266000, China.
⁴ Interventional Department, Zhangqiu District People's Hospital, Jinan 250200, China.
⁵ Department of Dermatology Laboratory, Qilu Hospital (Qingdao) Cheeloo College of Medicine, Shandong University, Qingdao 266035, China.

Abstract

Objective: To explore the curative effect of Wenshentiaojing Decoction on the treatment of menstrual disorder caused by PCOS.

Methods: Patients with menstrual disorders caused by PCOS admitted to our department from January 2020 to January 2021 were selected as the research objects and were divided into a control group and observation group according to the random number table method. The control group was treated with Western medicine, and the observation group was treated with Wenshentiaojing Decoction on the basis of Western medicine. The clinical efficacy of the two groups was compared. Before and after treatment, sex hormones (LH, FSH, LH/FSH, and testosterone (T)), ovarian volume, endometrial thickness, cervical mucus score, follicular number, menstrual conditions (menstrual duration, menstrual cycle, and menstrual volume), and other indicators in both groups were recorded.

Results: After treatment, the total effective rate of the observation group (91.1% (41/45)) was higher than that of the control group (77.8% (35/45)), and the difference was statistically significant (P < 0.05). After treatment, the LH, LH/FSH, and T levels in the observation group were lower than those in the control group, while the FSH level was higher than that in the control group (P < 0.05). After treatment, the ovarian volume, endometrial thickness, cervical mucus score, and follicle number in the observation group were higher than those in the control group (P < 0.05). After treatment, the menstrual duration and menstrual volume in the observation group were longer than those in the conventional group, and the menstrual cycle was shorter than that in the conventional group (P < 0.05).

Conclusion: For patients with menstrual disorders caused by PCOS, the treatment effect of Wenshentiaojing Decoction assisted with Western medicine is better, which can effectively improve the level of sex hormones, cervical mucus, and menstrual conditions, increase the ovarian volume, endometrial thickness, and follicle number, and improve the treatment effect, with fewer adverse reactions, which is worthy of further promotion and application.