Electrochemical regioselective C-H selenylation of 2 H-indazole derivatives

Org Biomol Chem. 2021 Dec 22;20(1):117-121. doi: 10.1039/d1ob02108g.

Abstract

Selenium-substituted heteroarenes are biologically active compounds and useful building blocks. In this study, we have developed a metal- and oxidant-free, environmentally friendly protocol for the regioselective selenylation of 2H-indazole derivatives by an electrochemical strategy. A number of selenylated 2H-indazoles with a wide range of functional groups have been synthesized in moderate to good yields under mild and environment-friendly reaction conditions.

Publication types

  • Research Support, Non-U.S. Gov't