Nanotechnology for Targeted Therapy of Atherosclerosis

Seyedmehdi Hossaini Nasr; Xuefei Huang

doi:10.3389/fphar.2021.755569

Nanotechnology for Targeted Therapy of Atherosclerosis

Front Pharmacol. 2021 Nov 12:12:755569. doi: 10.3389/fphar.2021.755569. eCollection 2021.

Authors

Seyedmehdi Hossaini Nasr^{1

2}, Xuefei Huang^{1

2

3}

Affiliations

¹ Department of Chemistry, Michigan State University, East Lansing, MI, United States.
² Institute for Quantitative Health Science and Engineering, Michigan State University, East Lansing, MI, United States.
³ Department of Biomedical Engineering, Michigan State University, East Lansing, MI, United States.

Abstract

Atherosclerosis is the major cause of heart attack and stroke that are the leading causes of death in the world. Nanomedicine is a powerful tool that can be engineered to target atherosclerotic plaques for therapeutic and diagnosis purposes. In this review, advances in designing nanoparticles with therapeutic effects on atherosclerotic plaques known as atheroprotective nanomedicine have been summarized to stimulate further development and future translation.

Keywords: atherosclerosis; drug delivery; inflammation; nanomedicine; statins.

Publication types

Review

Grants and funding

R01 GM072667/GM/NIGMS NIH HHS/United States