[Treatment for acute leukemia showing PCR-positivity of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) at initial diagnosis: a case report and review of literature]

Rinsho Ketsueki. 2021;62(11):1604-1608. doi: 10.11406/rinketsu.62.1604.
[Article in Japanese]

Abstract

The novel coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is rapidly spreading across the world. We encountered two patients with COVID-19 who underwent treatment for acute leukemia at initial diagnosis. Both the patients received conventional induction therapy without the exacerbation of COVID-19. Although the impact of SARS-CoV-2 on the treatment of leukemia is unclear, our treatment experience suggests that there is no major contraindication to standard chemotherapy for acute leukemia in patients with COVID-19. As COVID-19 continues to be a threat worldwide, further evaluations of large cohorts are needed for future treatment decisions for acute leukemia with COVID-19.

Keywords: Acute leukemia; COVID-19; Chemotherapy.

Publication types

  • Case Reports
  • Review

MeSH terms

  • COVID-19*
  • Humans
  • Leukemia*
  • Polymerase Chain Reaction
  • SARS-CoV-2