Aiphanol, a native compound, suppresses angiogenesis via dual-targeting VEGFR2 and COX2

Signal Transduct Target Ther. 2021 Dec 3;6(1):413. doi: 10.1038/s41392-021-00739-5.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cyclooxygenase 2 / metabolism*
  • Cyclooxygenase 2 Inhibitors / pharmacology*
  • Human Umbilical Vein Endothelial Cells / metabolism*
  • Humans
  • Neovascularization, Pathologic / drug therapy*
  • Neovascularization, Pathologic / metabolism
  • Stilbenes / pharmacology*
  • Vascular Endothelial Growth Factor Receptor-2 / antagonists & inhibitors*
  • Vascular Endothelial Growth Factor Receptor-2 / metabolism

Substances

  • Cyclooxygenase 2 Inhibitors
  • Stilbenes
  • aiphanol
  • Cyclooxygenase 2
  • PTGS2 protein, human
  • KDR protein, human
  • Vascular Endothelial Growth Factor Receptor-2