Subdistrict-Level Reproductive Number for Foot and Mouth Disease in Cattle in Northern Thailand

Orapun Arjkumpa; Catalina Picasso-Risso; Andres Perez; Veerasak Punyapornwithaya

doi:10.3389/fvets.2021.757132

Subdistrict-Level Reproductive Number for Foot and Mouth Disease in Cattle in Northern Thailand

Front Vet Sci. 2021 Nov 10:8:757132. doi: 10.3389/fvets.2021.757132. eCollection 2021.

Authors

Orapun Arjkumpa¹, Catalina Picasso-Risso², Andres Perez², Veerasak Punyapornwithaya^{3

4}

Affiliations

¹ Animal Health Section, The 4th Regional Livestock Office, Department of Livestock Development, Khon Kaen, Thailand.
² Department of Veterinary Population Medicine, University of Minnesota, St. Paul, MN, United States.
³ Faculty of Veterinary Medicine, Veterinary Public Health Centre for the Asia Pacific, Chiang Mai University, Chiang Mai, Thailand.
⁴ Faculty of Veterinary Medicine, Center of Excellence in Veterinary Public Health, Chiang Mai University, Chiang Mai, Thailand.

Abstract

Foot and mouth disease (FMD) is an important contagious transboundary disease that causes a significant economic loss for several countries. The FMD virus (FMDV) can spread very rapidly by direct and indirect transmission among susceptible animals. The complexity and magnitude of FMDV transmission at the initial stages of the epidemic can be expressed by the basic reproductive number (R ₀), and furthermore, control strategies can be assessed by the estimation of the effective reproductive number. In this study, we aimed to describe FMD outbreaks among smallholder cattle farms by subdistricts in the northern Thailand and compute the effective reproductive number for outbreaks caused by FMDV serotype O and overall serotypes, including serotype O, serotype A, and unidentified serotype, at the subdistrict level (R _sd ) using an epidemic doubling time method. Field data of FMD outbreaks during 2015-2017 that affected 94 subdistricts in northern Thailand were assessed to estimate the R _sd . Results showed that 63.38% (90/142) of the FMD outbreak episodes in cattle were caused by FMDV serotype O. The average doubling time and the R _sd estimated of the outbreaks caused by FMDV serotype O and overall serotype were 2.80 and 4.67 months, and 1.06 and 1.04, respectively. Our results indicated that transmission of FMD in cattle at the subdistrict level in northern Thailand was not controlled (R _sd > 1), which indicates the endemicity of the disease in the region. Although control measures are in place, the results from this study highlighted the need for enhancing FMD monitoring and control strategies in northern Thailand.

Keywords: cattle; foot and mouth disease; northern Thailand; serotype O; subdistrict reproductive number.