The effects of baths and wet wraps with a sweet whey solution on the level of hydration and barrier function of the epidermis

Postepy Dermatol Alergol. 2021 Oct;38(5):798-803. doi: 10.5114/ada.2021.110078. Epub 2021 Nov 5.

Abstract

Introduction: Sweet whey is known for its various pharmacological uses as an anti-inflammatory and antioxidant agent. This is because whey proteins accelerate the release of bioactive peptides, increase the level of intracellular glutathione and the production of interleukin IL-8. However, the potential skin care effects of whey, especially in its unprocessed state, are still not clear.

Aim: To evaluate in vivo the cosmetic features of sweet whey baths and wet wraps on human skin.

Material and methods: Thirteen healthy Caucasian adult females with no dermatological diseases were examined. We used the Courage-Khazaka MPA-9 device to evaluate the effects of sweet whey baths/wet wraps on skin hydration, transepidermal water loss (TEWL) and melanin and erythema index and pH level in human skin.

Results: It appeared that bathing in the sweet whey solution significantly improved the barrier function of the skin in comparison with tap water treated control area on the face cheek as well as on the forearm by decreasing the value of transepidermal water loss with statistical significance. Skin hydration was enhanced only on the facial skin. No significant differences concerning other parameters were observed.

Conclusions: We showed that sweet whey may have decreased the TEWL level and fixed the barrier function of epidermis in this way. It seems that a bath solution with sweet whey is well tolerated and may promote local blood circulation without affecting the pH value of the skin.

Keywords: human skin; hydration; transepidermal water loss; whey.