Biological evaluation of selective laser melted magnesium alloy powder

Acta Bioeng Biomech. 2021;23(1):121-133.

Abstract

Purpose: The current study examined magnesium alloy AZ31B specimens manufactured with Additive Manufacturing method (selective laser melting - SLM) to investigate the applicability of this technology for the production of medical devices.

Methods: Osteoblast cells and bacterial biofilm growth ability on specimen was examined and the effect of surface state on corrosion resistance was evaluated by electrochemical and immersion methods.

Results: High survival of hFOB cells, as well as a strong tendency for Pseudomonas aeruginosa and Staphylococcus aureus biofilm proliferation on the surface of the tested specimens were shown. SLM-processed AZ31B alloy has a higher corrosion resistance in 0.9% NaCl solution and in a multi-electrolyte saline solution than the material in a conventional form of a rolled sheet.

Conclusions: It has been demonstrated that the strong development of the surface of as-built processed specimens results in a significantly increased corrosion rate, which hinders the production of complex structures in tissue engineering products that support cell ingrowth.

MeSH terms

  • Alloys* / pharmacology
  • Corrosion
  • Lasers
  • Magnesium* / pharmacology
  • Powders

Substances

  • Alloys
  • Powders
  • Magnesium