Study on the use of standard 12-lead ECG data for rhythm-type ECG classification problems

Comput Methods Programs Biomed. 2022 Feb:214:106521. doi: 10.1016/j.cmpb.2021.106521. Epub 2021 Nov 10.

Abstract

Background and objectives: Most deep-learning-related methodologies for electrocardiogram (ECG) classification are focused on finding an optimal deep-learning architecture to improve classification performance. However, in this study, we proposed a methodology for fusion of various single-lead ECG data as training data in the single-lead ECG classification problem.

Methods: We used a squeeze-and-excitation residual network (SE-ResNet) with 152 layers as the baseline model. We compared the performance of a 152-layer SE-ResNet trained on ECG signals from various leads of a standard 12-lead ECG system to that of a 152-layer SE-ResNet trained on only single-lead ECG data with the same lead information as the test set. The experiments were performed using five different types of rhythm-type single-lead ECG data obtained from Konkuk University Hospital in South Korea.

Results: Experiment results based on the combination from the relationship experiments of the leads showed that lead -aVR or II revealed the best classification performance. In case of -aVR, this model achieved a high F1 score for normal (98.7%), AF (98.2%), APC (95.1%), and VPC (97.4%), indicating its potential for practical use in the medical field.

Conclusion: We concluded that the 152-layer SE-ResNet trained by fusion of single-lead ECGs had better classification performance than the 152-layer SE-ResNet trained on only single-lead ECG data, regardless of the single-lead ECG signal type. We also found that the best performance directions for single-lead ECG classification are Lead -aVR and II.

Keywords: 12 Single-lead ECG; Convolutional neural network; Deep learning; Heterogeneous single-lead ECG; SE-ResNet; Single-lead ECG classification; Standard 12-lead ECG.

MeSH terms

  • Algorithms*
  • Electrocardiography
  • Humans
  • Neural Networks, Computer*
  • Republic of Korea