Exercise and Mitochondrial Function: Importance and Inference- A Mini Review

Vaishali K; Nitesh Kumar; Vanishree Rao; Rakesh Krishna Kovela; Mukesh Kumar Sinha

doi:10.2174/1566524021666211129110542

Exercise and Mitochondrial Function: Importance and Inference- A Mini Review

Curr Mol Med. 2022;22(9):755-760. doi: 10.2174/1566524021666211129110542.

Authors

Vaishali K¹, Nitesh Kumar², Vanishree Rao³, Rakesh Krishna Kovela⁴, Mukesh Kumar Sinha¹

Affiliations

¹ Department of Physiotherapy, Manipal College of Health Professions, Manipal Academy of Higher Education, Manipal, Karnataka 576104, India.
² Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, Hajipur, Bihar, India.
³ Department of Pharmacology, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, India.
⁴ Department of Neurophysiotherapy, Ravi Nair Physiotherapy College, Datta Meghe Institute of Medical Sciences, Sawangi (Meghe), Wardha, Maharashtra 442001, India.

PMID: 34844538
DOI: 10.2174/1566524021666211129110542

Abstract

Skeletal muscles must generate and distribute energy properly in order to function perfectly. Mitochondria in skeletal muscle cells form vast networks to meet this need, and their functions may improve as a result of exercise. In the present review, we discussed exercise-induced mitochondrial adaptations, age-related mitochondrial decline, and a biomarker as a mitochondrial function indicator and exercise interference.

Keywords: Skeletal muscle; aging; biomarker; endurance exercise; mitochondrial activity; strength training.

Publication types

Review

MeSH terms

Adaptation, Physiological / physiology
Exercise* / physiology
Mitochondria*
Muscle Fibers, Skeletal
Muscle, Skeletal / metabolism