[Primary Liver Cancers - Hepatocellular Carcinoma and Cholangiocarcinoma]

Ther Umsch. 2021;78(10):585-588. doi: 10.1024/0040-5930/a001314.
[Article in German]

Abstract

Primary Liver Cancers - Hepatocellular Carcinoma and Cholangiocarcinoma Abstract. Malignant liver tumors are often discovered as an incidental finding on sonography. Hepatocellular carcinoma (HCC) is the most common primary liver malignancy, followed by cholangiocellular carcinoma (CCC). The most employed diagnostic tests are MRI with gadolinium contrast medium or 3-phase CT abdomen. Biopsy of a hepatic nodule can be omitted if the radiologic and clinical presentation are typical. Patients with malignant liver tumors and / or unclear findings should present to a liver center. The most effective therapies for HCC and CCC include liver resection and liver transplantation. Only surgical oncologic R0 resection is curative. The therapy should be done by a multidisciplinary team. If primary surgery of the lesion is not possible, interventional or sytemic chemotherapy can also be helpful.

Zusammenfassung. Lebertumoren werden häufig als Zufallsbefund in der Sonographie entdeckt. Weiterführende Diagnostik sind das MRT mit Gadolinium-Kontrastmittel oder das 3-Phasen-Abdomen-CT. Auf eine Biopsie bei einem Leberrundherd kann bei genauer Kenntnis der radiologischen und klinischen Präsentation verzichtet werden. Patienten mit Lebereigenen Tumoren und / oder unklaren Befunden sollten in einem Leberzentrum vorgestellt werden. Nur die chirurgisch-onkologische R0-Resektion ist kurativ.

MeSH terms

  • Bile Duct Neoplasms* / diagnosis
  • Bile Duct Neoplasms* / therapy
  • Bile Ducts, Intrahepatic
  • Carcinoma, Hepatocellular* / diagnosis
  • Carcinoma, Hepatocellular* / therapy
  • Cholangiocarcinoma* / diagnosis
  • Cholangiocarcinoma* / therapy
  • Humans
  • Liver Neoplasms* / diagnosis
  • Liver Neoplasms* / therapy