Antenatal magnesium sulphate for preventing cerebral palsy: An economic evaluation of the impact of a quality improvement program

Aust N Z J Obstet Gynaecol. 2022 Feb;62(1):168-171. doi: 10.1111/ajo.13459. Epub 2021 Nov 29.

Abstract

Previous work demonstrated that implementing a quality improvement (QI) program improves the uptake of guideline-recommended antenatal magnesium sulphate, a critical intervention known to reduce cerebral palsy risk. Here we estimate potential cost savings attributable to the improved uptake. By expanding coverage from 63 to 83% of eligible women, we estimated that five children potentially would not have received a diagnosis of cerebral palsy, a potential cost saving of $AU4.8 million in lifetime healthcare costs. Our findings strengthen the case for embedding QI approaches in perinatal care to reduce the incidence of cerebral palsy.

Keywords: cerebral palsy; cost-benefit analysis; magnesium sulphate; quality improvement.

MeSH terms

  • Cerebral Palsy* / prevention & control
  • Child
  • Cost-Benefit Analysis
  • Female
  • Humans
  • Magnesium Sulfate / therapeutic use
  • Neuroprotective Agents*
  • Pregnancy
  • Premature Birth* / prevention & control
  • Quality Improvement

Substances

  • Neuroprotective Agents
  • Magnesium Sulfate