Polyophthalmus zhadanae sp. nov. (Annelida, Opheliidae), is described from the coast of Kuwait and Saudi Arabia (Arabian Gulf) after specimens collected in the intertidal and shallow subtidal. This new species is characterised by the body pigmentation pattern, distribution of lateral eyes, presence of small dorsal and ventral parapodial cirri and pygidial features. External and internal anatomy was described after examination with SEM and micro-CT. The presence of several body structures in the genus such as a cephalic palpode-like papilla is discussed. Furthermore, the diversity of genus Polyophthalmus and the presence of Polyophthalmus pictus (Dujardin, 1839) in the Indo-Pacific is reviewed and a key to species is provided.