Nanomedicine for the Diagnosis and Therapy of COVID-19

Yingruo Wang; Yuanping Hao; Shunxin Fa; Weiping Zheng; Changqing Yuan; Wanchun Wang

doi:10.3389/fbioe.2021.758121

Nanomedicine for the Diagnosis and Therapy of COVID-19

Front Bioeng Biotechnol. 2021 Nov 4:9:758121. doi: 10.3389/fbioe.2021.758121. eCollection 2021.

Authors

Yingruo Wang¹, Yuanping Hao², Shunxin Fa^{3

4}, Weiping Zheng^{5

3}, Changqing Yuan^{5

3}, Wanchun Wang²

Affiliations

¹ Shandong University of Science and Technology, Qingdao, China.
² Qingdao Stomatological Hospital Affiliated to Qingdao University, Qingdao, China.
³ School of Stomatology, Qingdao University, Qingdao, China.
⁴ York School, Monterey, CA, United States.
⁵ Department of Stomatology, The Affiliated Hospital of Qingdao University, Qingdao, China.

Abstract

The coronavirus disease-2019 (COVID-19) pandemics caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been spreading around the world due to its high infection rate, long incubation period, as well as lack of effective diagnosis and therapy or vaccines, which is tearing global health systems apart. It is an urgent demand for point-of-care diagnosis and effective treatment to prevent the spread of COVID-19. Currently, based on the rapid development of functional materials with unique physicochemical features through advanced fabrication and chemical modification, nanomaterials provide an emerging tool to detect SARS-CoV-2, inhibit the interplay in the virus and host cell interface, and enhance host immune response. In our manuscript, we summarized recent advances of nanomaterials for the diagnosis and therapy of COVID-19. The limitation, current challenges, and perspectives for the nano-diagnosis and nano-therapy of COVID-19 are proposed. The review is expected to enable researchers to understand the effect of nanomaterials for the diagnosis and therapy of COVID-19 and may catalyze breakthroughs in this area.

Keywords: COVID-19; SARS-CoV-2; advanced materials; nanomaterials; theranostic nanomedicine.

Publication types

Review