Transmission of toxigenic Corynebacterium ulcerans infection with airway obstruction from cats to a human

Acute Med Surg. 2021 Nov 12;8(1):e705. doi: 10.1002/ams2.705. eCollection 2021 Jan-Dec.

Abstract

Background: Infections caused by Corynebacterium ulcerans, a zoonotic pathogen, have been reported worldwide. This microorganism is known to produce the diphtheria toxin and cause diphtheria-like illness.

Case presentation: A 63-year-old woman with a history of diabetes and hypertension developed cold and flu-like symptoms, which gradually progressed into respiratory distress. Therefore, the patient was intubated for dyspnea with pseudomembrane formation. A toxin-producing strain of C. ulcerans was identified, also detected in the patient's domestic cats. Multilocus sequence typing confirmed all strains, including the patient's isolate, as ST337.

Conclusion: Multilocus sequence typing revealed zoonotic transmission of C. ulcerans from domestic cats to a human.

Keywords: Cat; diphtheria; pseudomembrane; toxigenic Corynebacterium ulcerans; zoonosis.

Publication types

  • Case Reports