Data on known anti-virals in combating CoVid-19

L Akshayaa; Thangavelu Lakshmi; Ezhilarasan Devaraj; Anitha Roy; S Raghunandhakumar; P Sivaperumal; Sheba David; Kamal Dua; Dinesh Kumar Chellappan

doi:10.6026/97320630016878

Data on known anti-virals in combating CoVid-19

Bioinformation. 2020 Nov 30;16(11):878-881. doi: 10.6026/97320630016878. eCollection 2020.

Authors

L Akshayaa¹, Thangavelu Lakshmi¹, Ezhilarasan Devaraj¹, Anitha Roy¹, S Raghunandhakumar¹, P Sivaperumal¹, Sheba David², Kamal Dua^{3

4}, Dinesh Kumar Chellappan⁵

Affiliations

¹ Department of Pharmacology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai-600077, TamilNadu.
² PAPRSB Institute of Health Sciences, Universiti Brunei Darussalam, Brunei.
³ Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, Ultimo, NSW, 2007, Australia.
⁴ School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle NSW 2308,Australia.
⁵ Department of Life sciences, School of Pharmacy, International Medical University ,Bukit Jalil, 57000, Kualalumpur, Malaysia.

Abstract

Design and development of effective anti-virals in combating CoVid-19 is a great challenge worldwide. Known drugs such as chloroquine, lopinavir, favipiravir and remdesivir are used in the management of CoVid - 19. It is known that Ivermectin and remdesivir both are effective against filoviruses, paramyxo viruses. Available data also shows that ivermectin and remedesivir repress the replication of SARS-CoV-2. Thus, we document the potential use of ivermectin and remdesivir in the management of CoVid -19.

Keywords: COVID -19; SARS-Cov2; antiviral; ivermectin; remdesir.