Effects of Bacterial Metabolites on the Immune System: Enemies and Friends

Endocr Metab Immune Disord Drug Targets. 2022;22(12):1167-1177. doi: 10.2174/1871530321666211119150231.

Abstract

Metabolites produced by bacteria can influence the immune system. These metabolites are produced by pathogenic bacteria as well as the friendly microbiota. This review sheds light on the major bacterial metabolites and their structures. It also describes the capacity of these molecules to stimulate and inhibit the immune responses in a way that affects their capacity to control different diseases.

Keywords: Metabolites; bacteria; disease; immune; microbiota; pathogenic.

Publication types

  • Review

MeSH terms

  • Bacteria
  • Friends*
  • Humans
  • Immune System
  • Microbiota* / physiology