Multidrug-Resistant Infections in the Developing World

Pediatr Clin North Am. 2022 Feb;69(1):141-152. doi: 10.1016/j.pcl.2021.09.003.

Abstract

Antimicrobials are essential in reducing morbidity and mortality from infectious diseases globally. However, due to the lack of effective surveillance measures and widespread overuse, there is an increasing threat to the effectiveness of antimicrobials. Although there is a global increase in antimicrobial resistance, low- and middle-income countries share a much higher burden. Antimicrobial stewardship efforts such as effective surveillance and reduction in overuse can help combat the increase in antimicrobial resistance.

Keywords: AMR; Antimicrobial resistance; Global antimicrobial use; LMIC; Multidrug resistant.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Adult
  • Anti-Bacterial Agents / economics
  • Anti-Bacterial Agents / therapeutic use
  • Anti-Infective Agents / economics
  • Anti-Infective Agents / therapeutic use
  • Antimicrobial Stewardship*
  • COVID-19 / microbiology
  • Child
  • Child, Preschool
  • Developing Countries
  • Drug Resistance, Microbial*
  • Drug Resistance, Multiple, Bacterial
  • Female
  • Gastrointestinal Diseases / drug therapy
  • Global Health*
  • Gonorrhea / drug therapy
  • Humans
  • Infant
  • Infant, Newborn
  • Infections* / drug therapy
  • Infections* / epidemiology
  • Male
  • Sepsis / drug therapy
  • Young Adult

Substances

  • Anti-Bacterial Agents
  • Anti-Infective Agents