[In vitro comparative activity of norfloxacin in the comparison of pathogenic bacteria of the urinary tract]

Abstract

In this study 411 bacterial isolates from clinical urinary tract infections against some quinolones, azthreonam and trimethoprim + sulfamethoxazole combination were tested. Bactericidal kinetics of norfloxacin , cinoxacin and azthreonam against E. coli ATCC 25922 was determined. Both MICs values and bactericidal activities have shown that fluoroquinolones are more active against all Gram-positive and Gram-negative bacteria tested than the other drugs.