COBREXA.jl: constraint-based reconstruction and exascale analysis

Bioinformatics. 2022 Jan 27;38(4):1171-1172. doi: 10.1093/bioinformatics/btab782.

Abstract

Summary: COBREXA.jl is a Julia package for scalable, high-performance constraint-based reconstruction and analysis of very large-scale biological models. Its primary purpose is to facilitate the integration of modern high performance computing environments with the processing and analysis of large-scale metabolic models of challenging complexity. We report the architecture of the package, and demonstrate how the design promotes analysis scalability on several use-cases with multi-organism community models.

Availability and implementation: https://doi.org/10.17881/ZKCR-BT30.

Supplementary information: Supplementary data are available at Bioinformatics online.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Computing Methodologies*
  • Models, Biological
  • Software*