Focal nodular hyperplasia associated with a giant hepatocellular adenoma: A case report and review of literature

World J Hepatol. 2021 Oct 27;13(10):1450-1458. doi: 10.4254/wjh.v13.i10.1450.

Abstract

Background: Focal nodular hyperplasia (FNH) and hepatocellular adenoma (HCA) are well-known benign liver lesions. Surgical treatment is usually chosen for symptomatic patients, lesions more than 5 cm, and uncertainty of diagnosis.

Case summary: We described the case of a large liver composite tumor in an asymptomatic 34-year-old female under oral contraceptive for 17-years. The imaging work-out described two components in this liver tumor; measuring 6 cm × 6 cm and 14 cm × 12 cm × 6 cm. The multidisciplinary team suggested surgery for this young woman with an unclear HCA diagnosis. She underwent a laparoscopic left liver lobectomy, with an uneventful postoperative course. Final pathological examination confirmed FNH associated with a large HCA. This manuscript aimed to make a literature review of the current management in this particular situation of large simultaneous benign liver tumors.

Conclusion: The simultaneous presence of benign composite liver tumors is rare. This case highlights the management in a multidisciplinary team setting.

Keywords: Case report; Composite tumor; Focal nodular hyperplasia; Hepatocellular adenoma; Liver; Video vignette.

Publication types

  • Case Reports