Solution of Simultaneous Higher Order Equations Based on DNA Strand Displacement Circuit

IEEE Trans Nanobioscience. 2022 Oct;21(4):511-519. doi: 10.1109/TNB.2021.3128393. Epub 2022 Sep 26.

Abstract

Currently, DNA strand displacement is often used to build neural networks or solve logical problems. While there are few studies on the use of DNA strand displacement to solve the higher order equations. In this paper, the catalysis, degradation, annihilation and adjusted reaction modules are built through DNA strand displacement. The chemical reaction networks of the corresponding higher order equations and simultaneous equations are established through these modules, and these chemical reaction networks can be used to build analog circuits to solve binary primary simultaneous equations and binary quadratic simultaneous equations. Finally, through Visual DSD software verification, this design can realize the solution of binary primary simultaneous equations and binary quadratic simultaneous equations, which provides a reference for DNA computation in the future.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Catalysis
  • Computers, Molecular*
  • DNA* / metabolism
  • Logic

Substances

  • DNA