AIE-MOF materials for biological applications

Tahir Mehmood; J Prakasha Reddy

doi:10.1016/bs.pmbts.2021.06.013

AIE-MOF materials for biological applications

Prog Mol Biol Transl Sci. 2021:185:179-198. doi: 10.1016/bs.pmbts.2021.06.013. Epub 2021 Jul 20.

Authors

Tahir Mehmood¹, J Prakasha Reddy²

Affiliations

¹ Department of Chemistry, School of Sciences, Indrashil University, Rajpur, Gujarat, India.
² Department of Chemistry, School of Sciences, Indrashil University, Rajpur, Gujarat, India. Electronic address: j.prakashareddy@gmail.com.

PMID: 34782104
DOI: 10.1016/bs.pmbts.2021.06.013

Abstract

Metal-Organic Frameworks (MOFs), coming under the realm of coordination chemistry, are unparalleled and the most studied among the group of porous materials. Structurally, these are well-defined three-dimensional crystalline products that can be tuned for various potential applications with a range of physico-chemical properties. More recently, aggregation-induced emission (AIE) and AIE of MOF material has attracted tremendous attention due to promising applications in biology. However, a chapter summarizing the work in AIE-MOFs materials has never been reported till date. A comprehensive review on the AIE and MOFs separately is beyond the reach of this chapter. Hence, we have summarized overview of recent developments in the syntheses and biological applications such as cell imaging, heparin detection, and drug delivery. In the end, conclusion, prospects and challenges in the arena of AIE-MOF materials are also highlighted.

Keywords: AIE; Biological applications; Electrostatic interactions; Ligands; MOFs; Metal salts.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Drug Delivery Systems
Metal-Organic Frameworks*
Porosity

Substances

Metal-Organic Frameworks