Brain tissue motion in acute hemorrhagic stroke using amplified MRI (aMRI)

Jonathan Ince; Andrea Lecchini-Visintini; Alanoud Almudayni; Mark A Horsfield; Joanne Wormleighton; Caroline Banahan; Emma M L Chung; Jatinder S Minhas

doi:10.1016/j.mri.2021.11.002

Brain tissue motion in acute hemorrhagic stroke using amplified MRI (aMRI)

Magn Reson Imaging. 2022 Feb:86:17-19. doi: 10.1016/j.mri.2021.11.002. Epub 2021 Nov 12.

Authors

Jonathan Ince¹, Andrea Lecchini-Visintini², Alanoud Almudayni³, Mark A Horsfield⁴, Joanne Wormleighton⁵, Caroline Banahan⁶, Emma M L Chung⁷, Jatinder S Minhas⁸

Affiliations

¹ Department of Cardiovascular Sciences, University of Leicester, Leicester, UK; University Hospitals of Leicester NHS Trust, Leicester, UK. Electronic address: ji62@leicester.ac.uk.
² Department of Cardiovascular Sciences, University of Leicester, Leicester, UK; School of Engineering, University of Leicester, Leicester, UK.
³ Department of Cardiovascular Sciences, University of Leicester, Leicester, UK; College of Applied Medical Sciences, Prince Sattam bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.
⁴ Xinapse Systems Ltd, Colchester, UK.
⁵ University Hospitals of Leicester NHS Trust, Leicester, UK.
⁶ Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.
⁷ Department of Cardiovascular Sciences, University of Leicester, Leicester, UK; University Hospitals of Leicester NHS Trust, Leicester, UK; NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK; School of Life Course Sciences, King's College London, London, UK.
⁸ Department of Cardiovascular Sciences, University of Leicester, Leicester, UK; University Hospitals of Leicester NHS Trust, Leicester, UK; NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK.

PMID: 34774985
DOI: 10.1016/j.mri.2021.11.002

Abstract

Brain tissue pulsates with each cardiac cycle, however the effect of disease on this natural motion is still unclear. Current literature mainly focuses on healthy brain tissue, with only limited studies looking at disease states such as Chiari malformation and acute ischemic stroke. This case report advances on recent literature by describing the case of a patient with an acute intracerebral hemorrhage and demonstrating an amplified MRI cine of the brain's motion. A clearer understanding of the effects of disease on brain motion may guide clinical application of pulsation measurement.

Keywords: Amplified magnetic resonance imaging; Brain tissue pulsation; Cine; Intracerebral hemorrhage.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Brain / diagnostic imaging
Cerebral Hemorrhage / complications
Cerebral Hemorrhage / diagnostic imaging
Hemorrhagic Stroke*
Humans
Ischemic Stroke*
Magnetic Resonance Imaging
Stroke* / complications
Stroke* / diagnostic imaging

Grants and funding

MC_PC_17171/MRC_/Medical Research Council/United Kingdom