Stratified psychiatry: Tomorrow's precision psychiatry?

Martijn Arns; Hanneke van Dijk; Jurjen J Luykx; Guido van Wingen; Sebastian Olbrich

doi:10.1016/j.euroneuro.2021.10.863

Stratified psychiatry: Tomorrow's precision psychiatry?

Eur Neuropsychopharmacol. 2022 Feb:55:14-19. doi: 10.1016/j.euroneuro.2021.10.863. Epub 2021 Nov 9.

Authors

Martijn Arns¹, Hanneke van Dijk¹, Jurjen J Luykx², Guido van Wingen³, Sebastian Olbrich⁴

Affiliations

¹ Research Institute Brainclinics, Brainclinics Foundation, Nijmegen, Netherlands; Department of Cognitive Neuroscience, Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, Netherlands.
² Research Institute Brainclinics, Brainclinics Foundation, Nijmegen, Netherlands; Department of Psychiatry, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands; Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center, Utrecht, Netherlands; Outpatient second opinion clinic, GGNet Mental Health, Warnsveld, Netherlands.
³ Department of Psychiatry, Amsterdam UMC, University of Amsterdam, Location AMC, Amsterdam Neuroscience, Netherlands.
⁴ Research Institute Brainclinics, Brainclinics Foundation, Nijmegen, Netherlands.

PMID: 34768212
DOI: 10.1016/j.euroneuro.2021.10.863

Abstract

Here we review the paradigm-change from one-size-fits-all psychiatry to more personalized-psychiatry, where we distinguish between 'precision psychiatry' and 'stratified psychiatry'. Using examples in Depression and ADHD we argue that stratified psychiatry, using biomarkers to facilitate patients to best 'on-label' treatments, is a more realistic future for implementing biomarkers in clinical practice.

Keywords: ADHD; Biomarker; Depression; EEG; Precision psychiatry; Stratified psychiatry.

Publication types

Review

MeSH terms

Biomarkers
Humans
Precision Medicine*
Psychiatry*

Substances

Biomarkers