TAp63 regulates bone remodeling by modulating the expression of TNFRSF11B/Osteoprotegerin

Cell Cycle. 2021 Nov;20(22):2428-2441. doi: 10.1080/15384101.2021.1985772. Epub 2021 Nov 11.

Abstract

MSC, mesenchymal stem cells; OPG, osteoprotegerin; RUNX2, Run-trelated transcription factor 2.

Keywords: P63; breast; mesenchymal stem cells; osteogenic differentiation; p53 family; prostate cancer.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bone Remodeling
  • Cell Differentiation
  • Mesenchymal Stem Cells* / metabolism
  • Osteogenesis
  • Osteoprotegerin* / genetics
  • Osteoprotegerin* / metabolism

Substances

  • Osteoprotegerin

Grants and funding

This work was supported by the Ministero della Salute [#PGR00961].