A case of adenoid cystic carcinoma of trachea: treatment complications and radiotherapy role

J Contemp Brachytherapy. 2021 Oct;13(5):588-592. doi: 10.5114/jcb.2021.109853. Epub 2021 Oct 8.

Abstract

Purpose: Adenoid cystic carcinoma (ACC) of trachea is a relatively rare malignant neoplasm, for which there is a lack of prospective clinical trials investigating treatment effectiveness. Most of the authors prefer surgical resection followed by post-operative radiation therapy in case of incomplete excision. There are no available prospective data on post-relapse treatment.

Case presentation: The current paper presents a case of tracheal ACC in a young woman, treated solely with surgical resection without radiotherapy due to postoperative neurological complications requiring additional diagnostics, management, and treatment. As a complication itself, spinal cord dysfunction after tracheal surgery is extremely rare, in which radical radiotherapy and brachytherapy were successfully administered after disease recurrence.

Conclusions: Lack of post-operative radiotherapy resulting from neurological complications could be a reason for ACC recurrence in our patient. Administration of radiotherapy after incomplete resection of recurrent disease may lead to long-term locoregional control.

Keywords: adenoid cystic carcinoma; radiotherapy; spinal cord dysfunction; tracheal tumors.

Publication types

  • Case Reports