Intra-Articular Tumors

Surg Pathol Clin. 2021 Dec;14(4):665-677. doi: 10.1016/j.path.2021.06.008. Epub 2021 Oct 7.

Abstract

The intra-articular space is a relatively rare site of occurrence of neoplastic diseases. The 2 distinct groups of clinicopathologic entities that exhibit an almost exclusive tropism for the joints are represented by synovial chondromatosis and tenosynovial giant cell tumors (TGCT). Synovial chondromatosis is a locally aggressive chondrogenic neoplasm that very rarely can show malignant behavior. TGCT occur in 2 main variants, the localized variant and the more locally aggressive diffuse type. Malignant TCGT is exceedingly rare and is characterized by significant rates of both local recurrence and metastatic spread.

Keywords: Articular space; Bone; Joint diseases; Mesenchymal tumors; Synovial chondromatosis; Tenosynovial giant cell tumors.

Publication types

  • Review

MeSH terms

  • Humans
  • Neoplasms*