Genetic polymorphisms of 16 X-STR loci analyzed in the Han population of Yunnan Province, Southwest China

Leg Med (Tokyo). 2022 Feb:54:101974. doi: 10.1016/j.legalmed.2021.101974. Epub 2021 Oct 9.

Abstract

To investigate the genetic diversity and forensic identification efficiency of X-chromosomal short tandem repeats (X-STRs) in the Yunnan Han population, 16 X-STRs in 415 Yunnan Han individuals (247 males and 168 females) were studied. A total of 137 alleles were detected, and all loci in the Yunnan Han population were highly polymorphic. The combined discrimination of males (PDm) and females (PDf) was 0.9999997769115 and 0.999999999999999999996, respectively. Interpopulation comparisons between the Yunnan Han population and 21 other populations showed that the evolutionary relationships between different groups with the same ethnic group or nearby geographic origins were closer. This study provides the first data on X-STR genetic polymorphisms in the Yunnan Han population and enriches the X-STR database for the Chinese Han population.

Keywords: Forensic parameters; Phylogenetic analyses; X-STR; Yunnan Han.

MeSH terms

  • China
  • Female
  • Gene Frequency
  • Genetics, Population*
  • Humans
  • Male
  • Microsatellite Repeats / genetics
  • Polymorphism, Genetic* / genetics