Comparison of 30-day mortality and readmission frequency in women versus men with acute myocardial infarction

Proc (Bayl Univ Med Cent). 2021 Jul 21;34(6):668-672. doi: 10.1080/08998280.2021.1945364. eCollection 2021.

Abstract

This study aimed to assess gender differences in hospitalization incidence, 30-day mortality, and 30-day readmission rates for acute myocardial infarction (AMI) in a Southwestern US medical center. Hospital billing records for AMI admissions were compiled from January 2013 to June 2019, resulting in a sample size of 2394. Billing data included gender, age, principal procedure, insurance status, principal diagnosis, and race/ethnicity. Multivariate logistic regression was used to estimate gender differences in mortality after adjustment for the aforementioned factors. Men were hospitalized for AMI over twice as frequently, yet women had higher AMI mortality than men (9.3% vs. 6.1%, P < 0.01). Female AMI patients were older on average and slightly less likely to undergo percutaneous transluminal coronary angioplasty than men. Thirty-day readmission rates did not differ by gender. In absolute terms, AMI hospitalizations and deaths are larger in number in men, but AMI hospitalizations more frequently end in death in women.

Keywords: Acute myocardial infarction; gender; mortality; sex.

Grants and funding

The authors wish to thank the Laura W. Bush Institute for Women’s Health for supporting this work with a 2017 Research Scholar Grant.