Predictors for Outcome and Complications Related to Urinary Diversion

Anticancer Res. 2021 Nov;41(11):5585-5591. doi: 10.21873/anticanres.15372.

Abstract

Background/aim: Predictors for complications such as insufficiency of intestinal anastomosis in urinary diversion and other risk factors are not well defined. We aimed to elucidate predictive factors for complications in urinary diversions based on preoperative comorbidities and major complications. A special focus was set on anastomosis insufficiency as a major complication.

Patients and methods: Preoperative comorbidities, postoperative complications, duration of hospital stay, and follow-up were analyzed in 317 patients with urinary diversion. The impact of preoperative comorbidities on diversion types was described and quantified as defined by the age-adjusted Charlson Comorbidity Index.

Results: Overall, 14.8% of patients showed anastomosis-related complications, most within the ileal conduit group (15.9% in the cohort). Severe complications (Clavien-Dindo Classification Score >IIIa) were found in smokers (p=0.046), and in patients with vascular diseases (p=0.007), a high American Society of Anaesthesiologists (ASA)-score (p=0.047), a R1- (p=0.009), as well as a pN1 (p=0.007) status.

Conclusion: Several independent predictors for several postoperative complications in urinary diversions were identified, which were independent of the diversion method.

Keywords: Comorbidities; complications; cystectomy; transitional cell carcinoma; urinary diversion.

Publication types

  • Multicenter Study

MeSH terms

  • Age Factors
  • Aged
  • Comorbidity
  • Cystectomy* / adverse effects
  • Databases, Factual
  • Female
  • Germany
  • Humans
  • Male
  • Middle Aged
  • Postoperative Complications / diagnosis
  • Postoperative Complications / etiology*
  • Retrospective Studies
  • Risk Assessment
  • Risk Factors
  • Severity of Illness Index
  • Time Factors
  • Treatment Outcome
  • Urinary Bladder Neoplasms / pathology
  • Urinary Bladder Neoplasms / surgery*
  • Urinary Diversion / adverse effects*