Comparison of osseointegration of Ti-Al6V4 and Ti-Al6Nb7 implants: An experimental study

J Oral Biol Craniofac Res. 2021 Oct-Dec;11(4):624-627. doi: 10.1016/j.jobcr.2021.09.012. Epub 2021 Sep 17.

Abstract

Objective: In this study we aimed to investigate bone-implant connections (BICs) with Ti-Al6V4 and Ti-Al6Nb7 alloys. Two types of surface morphology, resorbable blast material (RBM) and sandblasted and acid-etched surfaces (SLA), were used for implants.

Materials and methods: Thirty female Sprague Dawley rats aged 0.5-1 year were used. The rats were randomly separated into three groups: 1) Ti-Al6V4 RBM surface (n = 10), 2), Ti-Al6Nb7 RBM surface (n = 10), and 3) Ti-Al6Nb7 SLA (n = 10) surface implants were surgically integrated in femoral bones. The average roughness (Ra) values for these implants were 1-2 Ra. The rats were sacrificed four weeks after the surgical procedure. For each section, the BIC ratio (%) was determined as a percentage of the total implant surface that was in direct contact with the bone.

Results: The BIC ratio was found to be higher in the Ti-Al6Nb7 RBM and Ti-Al6Nb7 SLA groups than in the Ti-Al6V4 RBM group (p < 0.05). There was no statistically significant difference in the BIC ratios between the Ti-Al6Nb7 RBM and Ti-Al6Nb7 SLA groups (p > 0.05).

Conclusion: Ti-Al6Nb7 exhibited good biocompatibility with bone cells. Ti-Al6Nb7 alloy could be a candidate material for dental implant production.

Keywords: Resorbable blast material; Sandblasted and acid etched; Ti-Al6-Nb7; Ti–Al6–V4.