Tissue Engineering and Its Potential to Reduce Prostate Cancer Treatment Sequelae-Narrative Review

Jan Adamowicz; Luis Alex Kluth; Marta Pokrywczynska; Tomasz Drewa

doi:10.3389/fsurg.2021.644057

Tissue Engineering and Its Potential to Reduce Prostate Cancer Treatment Sequelae-Narrative Review

Front Surg. 2021 Oct 14:8:644057. doi: 10.3389/fsurg.2021.644057. eCollection 2021.

Authors

Jan Adamowicz¹, Luis Alex Kluth², Marta Pokrywczynska¹, Tomasz Drewa¹

Affiliations

¹ Chair of Urology, Department of Regenerative Medicine, Collegium Medicum, Nicolaus Copernicus University, Bydgoszcz, Poland.
² Department of Urology, University Hospital Frankfurt, Frankfurt am Main, Germany.

Abstract

Tissue engineering offers the possibility to overcome limitations of current management for postprostatectomy incontinence and ED. Developed in recent years biotechnological feasibility of mesenchymal stem cell isolation, in vitro cultivation and implantation became the basis for new cell-based therapies oriented to induce regeneration of adult tissue. The perspective to offer patients suffering from post-prostatectomy incontinence or erectile dysfunction minimal invasive one-time procedure utilizing autologous stem cell transplantation is desired management.

Keywords: incontenence; prostate cancer; stem cell; tissue engineering; urology.

Publication types

Review