Fast evolution of SARS-CoV-2 driven by deamination systems in hosts

Future Virol. 2021 Sep;16(9):587-590. doi: 10.2217/fvl-2021-0181. Epub 2021 Sep 10.

Authors

Yanping Zhang^{1

2}, Wen Jiang^{1

2}, Yan Li³, Xiaojie Jin^{1

2}, Xiaoping Yang^{1

2}, Pirun Zhang⁴, Wenqing Jiang^{1

2}, Bin Yin^{1

2}

Affiliations

¹ Department of Respiratory Diseases, Qingdao Haici Hospital, Shandong, China.
² The Affiliated Qingdao Hiser Hospital of Qingdao University, Qingdao, Shandong, China.
³ Department of Cardiology, Qingdao Center Hospital, Shandong, China.
⁴ College of Basic Medicine, Shandong University of Traditional Chinese Medicine, Shandong, China.

Abstract

As an RNA virus, the fast evolution of SARS-CoV-2 is driven by the extensive RNA deamination by the host cells.

Keywords: RNA deamination; RNA structure; SARS-CoV-2; evolution; natural selection.

© 2021 Future Medicine Ltd.

Publication types

Editorial