Success of microbial genes based transgenic crops: Bt and beyond Bt

Mol Biol Rep. 2021 Dec;48(12):8111-8122. doi: 10.1007/s11033-021-06760-9. Epub 2021 Oct 30.

Abstract

Transgenic technology could hold the key to help farmers to fulfill the ever increasing fast-paced global demand for food. Microbes have always wondered us by their potentials and thriving abilities in the extreme conditions. The use of microorganisms as a gene source in transgenic development is a promising option for crop improvement. The aforesaid approach has already for improving the characteristics of food, industrial, horticulture, and floriculture crops. Many transgenic crops containing microbial genes have been accepted by the farmers and consumers worldwide over the last few decades. The acceptance has brought remarkable changes in the status of society by providing food safety, economic, and health benefits. Among transgenic plants harboring microbial genes, Bacillus thuringiensis (Bt) based transgenic were more focused and documented owing to its significant performance in controlling insects. However, other microbial gene-based transgenic plants have also reserved their places in the farmer's field globally. Therefore, in this review, we have thrown some light on successful transgenic plants harboring microbial genes other than Bt, having application in agriculture. Also, we presented the role of microbial genetic element and product thereof in the inception of biotechnology and discussed the potential of microbial genes in crop improvement.

Keywords: Bacillus thuringiensis (Bt); Crop improvement; Genetic engineering; Microbial genetic element; Transgenic technology.

Publication types

  • Review

MeSH terms

  • Agriculture / trends*
  • Animals
  • Bacillus thuringiensis / genetics
  • Bacillus thuringiensis Toxins
  • Bacterial Proteins / genetics
  • Crops, Agricultural / genetics
  • Endotoxins
  • Genes, Microbial
  • Humans
  • Insecta / genetics
  • Insecticide Resistance
  • Pest Control, Biological / methods
  • Pest Control, Biological / trends*
  • Plants, Genetically Modified / genetics
  • Plants, Genetically Modified / metabolism*

Substances

  • Bacillus thuringiensis Toxins
  • Bacterial Proteins
  • Endotoxins