Brain tissue development of neonates with Congenital Septal Defect: Study on MRI Image Evaluation of Deep Learning Algorithm

Jianfei Zhu; Jiaolei Chen; Yunhui Zhang; Jianwei Ji

doi:10.12669/pjms.37.6-WIT.4863

Brain tissue development of neonates with Congenital Septal Defect: Study on MRI Image Evaluation of Deep Learning Algorithm

Pak J Med Sci. 2021;37(6):1652-1656. doi: 10.12669/pjms.37.6-WIT.4863.

Authors

Jianfei Zhu¹, Jiaolei Chen², Yunhui Zhang³, Jianwei Ji⁴

Affiliations

¹ Jianfei Zhu, Attending Physician. Department of Neonatology, Yiwu Central Hospital, Yiwu, 322000, China.
² Jiaolei Chen, Attending Physician. Department of Neonatology, Yiwu Central Hospital, Yiwu, 322000, China.
³ Yunhui Zhang, Attending Physician. Department of Neonatology, Yiwu Central Hospital, Yiwu, 322000, China.
⁴ Jianwei Ji, Attending Physician. Department of Neonatology, Yiwu Central Hospital, Yiwu, 322000, China.

Abstract

Objectives: This article is based on deep learning algorithms and uses MRI to study the development of congenital heart septal defects in neonatal brain tissue.

Methods: From January 2018 to December 2019, 150 cases of congenital cardiac paper septal defect were retrospectively analyzed on 50 cases of normal newborns and neonates. The four index parametersbrain MR imaging, lateral ventricle pre-angle measurement index (F/F'), body index (D/ D'), caudal nucleus index (C/C') were analyzed. The independent sample t test is performed to compare the difference parameters between groups.

Results: F congenital heart disease group and control group/F 'values were 0.301 ± 0.035 and 0.296 ± 0.031; Evans index was 0.239 ± 0.052 and 0.233 ± 0.025; 2 sets of D/D' values were 0.261 ± 0.039 and 0.234 ± 0.032; C/C 'value was 0.138 ± 0.018 and 0.124 ± 0.015 respectively. The congenital heart disease group D/D ', and the value of C/C' obtained under the ROC curve area value, respectively 0.698 and 0.750, Youden index corresponding to the maximum D/D ', and the value of C/C' values were 0.28 and 0.12.

Conclusion: Lateral ventricle D/D 'and C/C' is more sensitive indicator which can be evaluated with the difference between the volume of congenital heart septal defects in newborn normal neonatal brain; when the D/D 'value> 0.28, C/C' value> 0.12. For the diagnosis and evaluation of congenital heart septal defect neonatal brain volume abnormalities have a certain reference value.

Keywords: Brain Tissue; Congenital Septal Defect; Deep Learning Algorithm; MRI Image Evaluation; Neonates.