Ultrasound-guided percutaneous metal-organic frameworks based codelivery system of doxorubicin/acetazolamide for hepatocellular carcinoma therapy

Clin Transl Med. 2021 Oct;11(10):e600. doi: 10.1002/ctm2.600.

Authors

Ziwei Jing^{1

2}, Xiaohui Wang³, Na Li⁴, Zhi Sun¹, Dingding Zhang⁵, Lin Zhou¹, Fanxiang Yin⁶, Qingquan Jia¹, Mengli Wang¹, Yaojuan Chu¹, Shuzhang Du¹, Yaping He¹, Qiuzheng Du¹, Xiaojian Zhang¹

Affiliations

¹ Department of Pharmacy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
² School of Biological Science and Medical Engineering, Southeast University, Nanjing, China.
³ Department of Ultrasound, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
⁴ Department of Stomatology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
⁵ Department of Cardiovascular, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
⁶ Translational Medicine Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Acetazolamide / administration & dosage*
Acetazolamide / therapeutic use
Animals
Antibiotics, Antineoplastic / administration & dosage
Antibiotics, Antineoplastic / therapeutic use
Carbonic Anhydrase Inhibitors / administration & dosage
Carbonic Anhydrase Inhibitors / therapeutic use
Carcinoma, Hepatocellular / drug therapy*
Disease Models, Animal
Doxorubicin / administration & dosage*
Doxorubicin / therapeutic use
Drug Therapy, Combination
Liver / diagnostic imaging
Liver Neoplasms / drug therapy*
Metal-Organic Frameworks*
Rats
Rats, Sprague-Dawley
Ultrasonography, Interventional / methods*

Substances

Antibiotics, Antineoplastic
Carbonic Anhydrase Inhibitors
Metal-Organic Frameworks
Doxorubicin
Acetazolamide