Platelet Transfusion: An Update on Indications and Guidelines

Clin Lab Med. 2021 Dec;41(4):621-634. doi: 10.1016/j.cll.2021.07.005. Epub 2021 Sep 30.

Abstract

Platelets are commonly transfused either therapeutically or prophylactically to maintain hemostasis. Most platelet transfusions are used to manage patients with hematologic malignancies. Although platelet transfusion guidelines have been published, platelet transfusion practices are still heterogeneous. Platelet transfusion guidelines partly lack recommendations or differ in the platelet threshold recommendations in some clinical situations. This article reviews platelet transfusions focusing on transfusion guidelines and platelet thresholds in different clinical settings.

Keywords: Guidelines; Platelet transfusion; Prophylactic; Review; Therapeutic.

Publication types

  • Review

MeSH terms

  • Hemorrhage*
  • Humans
  • Platelet Transfusion*