Manganese Encephalopathy Caused by Homemade Methcathinone (Ephedrone) Prevalence in Poland

Nutrients. 2021 Oct 3;13(10):3496. doi: 10.3390/nu13103496.

Abstract

Manganese encephalopathy is a known disorder in occupational medicine. A serious phenomenon has been the emergence of manganese encephalopathy in intravenous users of homemade methcathinone (ephedrone). A short survey was developed for clinical environments dealing with people who use psychoactive substances. The data were obtained from 72 rehabilitation therapy centers. Surveys carried out in about a third of Polish centers dealing with providing medical assistance to people addicted to substances other than alcohol and tobacco have shown that over 4% of people treated there had symptoms of manganese encephalopathy, of which more than half are people in whom the probability of a clinical diagnosis of this disorder is significant. It has been shown that knowledge of manganese encephalopathy is none or minimal in more than 70% of the surveyed institutions. An urgent need for personnel training in this field was pointed out. Attention was paid to the importance of disseminating good review articles on new and dynamically developing problem phenomena.

Keywords: ephedrone; manganese encephalopathy; manganism; methcathinone; prevalence.

MeSH terms

  • Brain Diseases / chemically induced
  • Brain Diseases / epidemiology*
  • Humans
  • Manganese Poisoning / epidemiology*
  • Manganese Poisoning / etiology
  • Poland / epidemiology
  • Prevalence
  • Propiophenones*
  • Substance Abuse, Intravenous / complications
  • Substance Abuse, Intravenous / epidemiology*

Substances

  • Propiophenones
  • monomethylpropion