Molecular docking analysis of Enterotoxin I from Staphylococcus aureus with Nafcillin analogues

Jayaraman Selvaraj; Rajagopal Ponnulakshmi; Veeraraghavan Vishnupriya; Chandrasekar Kirubhanand

doi:10.6026/97320630016731

Molecular docking analysis of Enterotoxin I from Staphylococcus aureus with Nafcillin analogues

Bioinformation. 2020 Oct 31;16(10):731-735. doi: 10.6026/97320630016731. eCollection 2020.

Authors

Jayaraman Selvaraj¹, Rajagopal Ponnulakshmi², Veeraraghavan Vishnupriya¹, Chandrasekar Kirubhanand³

Affiliations

¹ Department of Biochemistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai - 600 077, India.
² Central Research Laboratory, Meenakshi Academy of Higher Education and Research (Deemed to be University), West K. K. Nagar, Chennai-600 078, India.
³ Department of Anatomy, All India Institute of Medical Sciences (AIIMS), Nagpur, India.

Abstract

Staphylococcal enterotoxins (SEs) are liked with food poisoning and other related infections. Nafcillin is an antibiotic used to treat S. aureus. Therefore, it is of interest to study the molecular interactions of 25 nafcillin analogues with enterotoxin I using molecular docking analysis. The analysis shows optimal interaction features of Nafcillin analogues with Enterotoxin I from Staphylococcus aureus for further consideration.

Keywords: Nafcillin; S aureus; enterotoxins I; molecular docking.