Poisoning of calves reared with cows treated with abamectin

Toxicon. 2021 Nov:203:115-116. doi: 10.1016/j.toxicon.2021.10.005. Epub 2021 Oct 15.

Abstract

The aim of the present study was to describe an outbreak of poisoning by abamectin in calves less than four months of age whose mothers were treated with a pour-on product containing this ingredient. The diagnosis was based on the history, clinical signs, absence of macroscopic and histopathological findings (characteristic of this type of poisoning) and the detection of abamectin in tissues of the animals submitted to necropsy. Based on this report, the recommendation is the use with caution of pour-on formulations containing abamectin on cows having given birth less than four months earlier.

Keywords: Macrocyclic lactones; Ruminants; Safety.

MeSH terms

  • Animals
  • Anthelmintics*
  • Cattle
  • Cattle Diseases* / chemically induced
  • Cattle Diseases* / drug therapy
  • Female
  • Ivermectin / analogs & derivatives
  • Ivermectin / toxicity

Substances

  • Anthelmintics
  • abamectin
  • Ivermectin