Photoacoustic assessment of the fetal brain and placenta as a method of non-invasive antepartum and intrapartum monitoring

Exp Neurol. 2022 Jan:347:113898. doi: 10.1016/j.expneurol.2021.113898. Epub 2021 Oct 15.

Abstract

A noninvasive monitor for concurrent evaluation of placental and fetal sagittal sinus sO 2 for both antepartum surveillance at the late 2nd and 3rd trimesters and intrapartum monitoring would be a great advantage over current methods. A PA fetal brain and placental monitor has potential value to rapidly identify the fetus at risk for developing hypoxia and ischemia of a sufficient degree that brain injury or death may develop, which may be prevented by intervention with delivery and other follow-up treatments.

Keywords: Fetal brain; Photoacoustics; Placenta.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Brain / blood supply
  • Brain / diagnostic imaging*
  • Brain / physiology
  • Cerebrovascular Circulation / physiology
  • Female
  • Fetal Hypoxia / diagnostic imaging
  • Fetal Hypoxia / physiopathology
  • Fetal Monitoring / methods*
  • Fetus / diagnostic imaging*
  • Fetus / physiology
  • Humans
  • Hypoxia-Ischemia, Brain / diagnostic imaging
  • Hypoxia-Ischemia, Brain / physiopathology
  • Photoacoustic Techniques / methods*
  • Placenta / blood supply
  • Placenta / diagnostic imaging*
  • Placenta / physiology
  • Pregnancy