The genome sequence of the Norway rat, Rattus norvegicus Berkenhout 1769

Kerstin Howe; Melinda Dwinell; Mary Shimoyama; Craig Corton; Emma Betteridge; Alexander Dove; Michael A Quail; Michelle Smith; Laura Saba; Robert W Williams; Hao Chen; Anne E Kwitek; Shane A McCarthy; Marcela Uliano-Silva; William Chow; Alan Tracey; James Torrance; Ying Sims; Richard Challis; Jonathan Threlfall; Mark Blaxter

doi:10.12688/wellcomeopenres.16854.1

The genome sequence of the Norway rat, Rattus norvegicus Berkenhout 1769

Wellcome Open Res. 2021 May 18:6:118. doi: 10.12688/wellcomeopenres.16854.1. eCollection 2021.

Authors

Kerstin Howe¹, Melinda Dwinell², Mary Shimoyama², Craig Corton¹, Emma Betteridge¹, Alexander Dove¹, Michael A Quail¹, Michelle Smith¹, Laura Saba³, Robert W Williams⁴, Hao Chen⁵, Anne E Kwitek², Shane A McCarthy^{1

6}, Marcela Uliano-Silva¹, William Chow¹, Alan Tracey¹, James Torrance¹, Ying Sims¹, Richard Challis¹, Jonathan Threlfall¹, Mark Blaxter¹

Affiliations

¹ Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SA, UK.
² Medical College of Wisconsin, Milwaukee, Wisconsin, 53226, USA.
³ Skaggs School of Pharmacy and Pharmaceutical Sciences,, University of Colorado Anschutz Medical Center, Aurora, Colorado, 80045, USA.
⁴ Department of Genetics, Genomics and Informatics, University of Tennessee Health Science Center, Memphis, Tennessee, 38103, USA.
⁵ Department of Pharmacology, Addiction Science, and Toxicology, University of Tennessee Health Science Center, Memphis, Tennessee, 38103, USA.
⁶ Department of Genetics, University of Cambridge, Cambridge, CB2 3EH, UK.

Abstract

We present a genome assembly from an individual male Rattus norvegicus (the Norway rat; Chordata; Mammalia; Rodentia; Muridae). The genome sequence is 2.44 gigabases in span. The majority of the assembly is scaffolded into 20 chromosomal pseudomolecules, with both X and Y sex chromosomes assembled. This genome assembly, mRatBN7.2, represents the new reference genome for R. norvegicus and has been adopted by the Genome Reference Consortium.

Keywords: Norway rat; Rattus norvegicus; chromosomal; genome sequence; reference genome.

Abstract

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