What happens to patients undergoing cancer surgery with psychiatric comorbidities?: A nationwide retrospective cohort study

J Surg Oncol. 2022 Mar;125(3):535-543. doi: 10.1002/jso.26716. Epub 2021 Oct 14.

Abstract

Objective: We aimed to describe the surgical outcomes and readmissions rates in patients with psychological comorbidities who underwent surgical intervention for cancer.

Background: The Hospital Readmission Reduction Program, a campaign by the Affordable Care Act, penalizes hospitals for greater readmission rates. One prevalent patient risk factor associated with hospital readmission is a comorbid psychiatric condition. Currently, no studies exist identifying psychiatric comorbidities and their effects on patients with cancer undergoing surgical intervention.

Methods: A cross-sectional analysis was performed using the Nationwide Readmissions Database for 2010-2014 and included adult patients undergoing cancer resection operations. Multivariable logistic regression analyses were utilized to assess determinants of surgical outcomes and readmissions.

Results: Of 1 016 636 eligible patients, 11.6% had psychiatric comorbidities. Patients with psychiatric disorders had greater risks of mortality (odds ratio [OR] = 1.21, 95% confidence interval [CI] = 1.18-1.25), complications (OR = 1.51, 95%CI = 1.50-1.52), extended length of stay (OR = 1.21, 95%CI = 1.20-1.22), and incurred healthcare expenditure at primary admission (OR = 1.16, 95% CI = 1.15-1.18). Psychiatric comorbidities were associated with an increased likelihood of readmission (OR = 1.13, 95%CI = 1.11-1.15).

Conclusions: Concomitant psychiatric conditions were attributed to poor surgical outcomes and a higher risk of readmissions. Multidisciplinary care within the perioperative setting should be encouraged for patients with psychiatric disorders.

Keywords: cancer; psychiatry; surgical outcomes.

MeSH terms

  • Aged
  • Cross-Sectional Studies
  • Female
  • Hospital Mortality
  • Hospitalization / statistics & numerical data
  • Humans
  • Logistic Models
  • Male
  • Mental Disorders / complications*
  • Middle Aged
  • Neoplasms / mortality
  • Neoplasms / psychology*
  • Neoplasms / surgery*
  • Outcome Assessment, Health Care
  • Postoperative Complications / epidemiology*
  • Postoperative Complications / psychology
  • Retrospective Studies
  • United States