Natural Polymers for the Maintenance of Oral Health: Review of Recent Advances and Perspectives

Int J Mol Sci. 2021 Sep 25;22(19):10337. doi: 10.3390/ijms221910337.

Abstract

The success of modern dental treatment is strongly dependent on the materials used both temporarily and permanently. Among all dental materials, polymers are a very important class with a wide spectrum of applications. This review aims to provide a state-of-the-art overview of the recent advances in the field of natural polymers used to maintain or restore oral health. It focuses on the properties of the most common proteins and polysaccharides of natural origin in terms of meeting the specific biological requirements in the increasingly demanding field of modern dentistry. The use of naturally derived polymers in different dental specialties for preventive and therapeutic purposes has been discussed. The major fields of application cover caries and the management of periodontal diseases, the fabrication of membranes and scaffolds for the regeneration of dental structures, the manufacturing of oral appliances and dentures as well as providing systems for oral drug delivery. This paper also includes a comparative characteristic of natural and synthetic dental polymers. Finally, the current review highlights new perspectives, possible future advancements, as well as challenges that may be encountered by researchers in the field of dental applications of polymers of natural origin.

Keywords: biomaterials; biopolymers; chitosan; collagen; dentistry; drug delivery; polymers; tissue engineering.

Publication types

  • Review

MeSH terms

  • Animals
  • Biocompatible Materials / pharmacology
  • Biological Products / pharmacology*
  • Humans
  • Oral Health
  • Periodontal Diseases / drug therapy
  • Polymers / pharmacology*
  • Regeneration / drug effects
  • Tissue Engineering / methods

Substances

  • Biocompatible Materials
  • Biological Products
  • Polymers